TLR family and viral infection

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Evolution of the Bovine TLR Gene Family and Member Associations with Mycobacterium avium Subspecies paratuberculosis Infection

Members of the Toll-like receptor (TLR) gene family occupy key roles in the mammalian innate immune system by functioning as sentries for the detection of invading pathogens, thereafter provoking host innate immune responses. We utilized a custom next-generation sequencing approach and allele-specific genotyping assays to detect and validate 280 biallelic variants across all 10 bovine TLR genes...

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ژورنال

عنوان ژورنال: Uirusu

سال: 2004

ISSN: 0042-6857,1884-3433

DOI: 10.2222/jsv.54.145